Yun-Sil Lee is an Associate Professor of Molecular Genetics at the Seoul National University School of Dentistry. She earned her D.D.S. from the Seoul National University School of Dentistry, followed by a Ph.D. from the Johns Hopkins University School of Medicine. She also completed a clinical research fellowship at the National Institutes of Health (NIH), specifically at the National Institute of Dental and Craniofacial Research (NIDCR).

Her research focuses on elucidating the cellular and molecular mechanisms underlying muscle and bone formation. This includes investigating signaling pathways mediated by myostatin and growth differentiation factor 11 (GDF11), two closely related members of the TGF-β superfamily. Despite their structural similarity, these factors play distinct roles in muscle regeneration and bone metabolism. Her lab currently focuses on the role of mitochondria in musculoskeletal regeneration. A recent study from her group, published in Cell Metabolism, revealed that mitochondria can be actively secreted into the extracellular space during bone formation, offering novel insights into their function in musculoskeletal regeneration.